Abstract Background To inform the development of a core outcome set (COS) for children and youth with mucopolysaccharidoses (MPS), we aimed to identify all outcomes and associated outcome measurement instruments that are reported in recent clinical trials and recommended as measurements in clinical management guidelines.Methods To identify English-
We investigated structure optimization, mechanical stability, electronic and bonding properties of the nanolaminate compounds Ti2PbC, Zr2PbC, and Hf2PbC using the first-principles calculations.These structures display nanolaminated edifices where MC layers are Cookbook interleaved with Pb.The calculation of formation energies, elastic moduli and ph
Background: With the outbreak of the coronavirus disease 2019 (COVID-19) epidemic in China, the general public but also cat toy medical staff were confronted with psychological challenges, suffering from the highly infectious and unknown characteristics of COVID-19.In this study, we surveyed psychological symptoms including anxiety, depression, and
Soft-tissue sarcomas (STS) are a group of rare, heterogeneous, and aggressive tumors, with high metastatic risk and relatively few efficient systemic therapies.In the quest for new treatments, the immune system represents an attractive therapeutic target.Recently, PD1/PDL1 inhibitors showed very promising results in patients with solid tumors.PDL1
The remodeling of the left atrial morphology and function caused by atrial fibrillation (AF) can exacerbate thrombosis in the left atrium (LA) even spike up the risk arrow tool of stroke within AF patients.This study explored the effect of the AF on hemodynamic and thrombosis in LA.We reconstructed the patient-specific anatomical shape of the LA an